| 货号 | 5027/50 |
| 别名 | 2-Aminobicyclo[2.2.1]heptane-2-carb |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 155.2 |
| 分子式 | C8H13NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Kimet al (2008) BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. Biol.Pharm.Bull. 31 1096. PMID: 18520037. Linet al (2004) L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma. Neoplasia 6 74. PMID: 15068672. Fragaet al(2002)L-type amino acid transporters in two intestinal epithelial cell lines function as exchangers with neutral amino acids. J.Nutr. 132 733. PMID: 11925469. |