| 货号 | 5038/50 |
| 别名 | 1H-Benzotriazol-1-amine |
| 供应商 | Tocris |
| 生物活性 | Cytochrome P450 inhibitor. Inhibits synthesis of the eicosanoid 20-hydroxyeicosatetraenoic acid (20-HETE). Reduces intimal hyperplasia and vascular remodeling following endothelial injury in rat carotid arteries. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 134.14 |
| 分子式 | C6H6N4 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Orozcoet al (2013) 20-hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries. J.Pharmacol.Exp.Ther. 346 67. PMID: 23658377. Mathewset al (1985) Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole. J.Pharmacol.Exp.Ther. 235 186. PMID: 4045721. |