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货号: bs-2456R 基本售价: 780.0 元 规格: 50ul
- 规格:50ul
- 价格:780.00元
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-2456R
- 英文名称
- TNFSF18
- 中文名称
- 肿瘤坏死因子配体超家族成员18抗体
- 别 名
- Tumor necrosis factor ligand superfamily member 18; AITRL; GITRL; hGITRL; TL6; Activation inducible TNF related ligand; AITR ligand ; AITRL; GITR ligand; ; Glucocorticoid induced TNF related ligand; Glucocorticoid induced TNFR related protein ligand; MGC138237; Tumor necrosis factor (ligand) superfamily member 18; GITR Ligand; TNF18_HUMAN.
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 细胞凋亡 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TNFSF18:101-199/199 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq].
Function:
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.
Subunit:
Homodimer. Homotrimer.
Subcellular Location:
Cell membrane; Single-pass type II membrane protein.
Tissue Specificity:
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Similarity:
Belongs to the tumor necrosis factor family.
SWISS:
Q9UNG2
Gene ID:
8995
Database links:Entrez Gene: 8995 Human
Entrez Gene: 240873 Mouse
Omim: 603898 Human
SwissProt: Q9UNG2 Human
SwissProt: Q7TS55 Mouse
Unigene: 248197 Human
Unigene: 276823 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
- Sample:
Testis (Mouse) Lysate at 40 ug
Primary: Anti-TNFSF18 (bs-2456R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 23 kD
Observed band size: 29 kD