| 货号 | 10380-1ea |
| 描述 | Histone H4 undergoes many modifications including acetylation, methylation, and phosphorylation, each important for regulation of gene transcription.1,2 This histone H4 peptide contains a lysine at position 20 which is a substrate or acceptor peptide for the lysine methyltransferases KMT5A (SET8) and KMT5B (SUV4-20H1).3,4 |
| 别名 | Histone H4K20 Peptide;SET8 Methyltransferase Acceptor Peptide; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kouzarides, T. Chromatin modifications and their function. Cell 128, 693-705 (2007). 2.Pennisi, E. Opening the way to gene activity. Science 275, 155-157 (1997). 3.Yin, Y.,Liu, C.,Tsai, S.N., et al. SET8 recognizes the sequence RHRK20VLRDN within the N terminus of histone H4 and mono-methylates lysine 20. The Journal of Biological Chemisty 280(34), 30025-30031 (2005). 4.Couture, J.F.,Collazo, E.,Brunzelle, J.S., et al. Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase. Genes & Development 19, 1455-1465 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 计算分子量 | 1278 |
| 稳定性 | ≥ 1 year |
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