Amyloid-β (1-8, A2V) Peptide
货号：
10229-1ea 基本售价：
854.0 元 规格：
1 ea
产品信息
概述| 货号 | 10229-1ea |
| 描述 | β-Amyloid peptide (1-42) aggregation results in the formation of neurotoxic fibrils or globular oligomers.1 The amyloid precursor protein (APP) mutation Ala673 → Val673 results in disease for homozygous carriers but not for heterozygous carriers. The mutation generates β-Amyloid peptide with valine at amino acid position two. Biochemical analysis of Aβ (1-42) aggregation suggests this small peptide may be a useful guide for developing β-amyloid peptide aggregation inhibitors.2 |
| 别名 | Aβ (1-8, A2V);Aβ (1-8) mutant;β-Amyloid (1-8) dominant negative; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wolfe, M.S. Therapeutic strategies for Alzheimer’s disease. Nature Reviews.Drug Discovery 1, 859-866 (2002).
2.Di Fede, G.,Catania, M.,Morbin, M., et al. A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. Science 323, 1473-1477 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 计算分子量 | 1004 |
| 稳定性 | ≥ 1 year |
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