| 货号 | 14291-500mg |
| 描述 | Hygromycin B is an antibiotic which is used in molecular and cell biology to select for transformed cells expressing the hygromycin resistance gene.1,2 It is an aminoglycoside produced by the bacterium S. hygroscopicus which kills prokaryotic and eukaryotic cells by inhibiting protein synthesis.3,4 The hygromycin resistance gene (hyg or hph) encodes a phosphotransferase which inhibits hygromycin through phosphorylation.2 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kaster, K.R.,Burgett, S.G.,Rao, R.N., et al. Analysis of a bacterial hygromycin B resistance gene by transcriptional and translational fusions and by DNA sequencing. Nucleic Acids Research 11(19), 6895-6911 (1983). 2.Blochlinger, K. and Diggelmann, H. Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cells. Molecular and Cellular Biology 4(12), 2929-2931 (1984). 3.Eustice, D.C. and Wilhelm, J.M. Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis. Antimicrobial Agents and Chemotherapy 26(1), 53-60 (1984). 4.Cabañas, M.J.,Vázquez, D. and Modolell, J. Dual interference of hygromycin B with ribosomal translocation and with aminoacyl-tRNA recognition. European Journal of Biochemistry 87, 21-27 (1978). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥85% |
| 计算分子量 | 527.5 |
| 分子式 | C20H37N3O13 |
| CAS号 | 31282-04-9 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |