Z-VAD(OH)-FMK
货号:
14467-500ug 基本售价:
826.0 元 规格:
500 ug
产品信息
概述货号 | 14467-500ug |
描述 | Z-VAD(OH)-FMK is an irreversible tripeptide inhibitor of all caspases.1,2,3 This non-methylated form is useful in studies involving recombinant, isolated, or purified enzymes. Unlike the methylated form, Z-VAD(OMe)-FMK (Item No. 14463), this compound does not require pretreatment with esterases prior to in vitrouse. |
别名 | Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone; |
性能供应商 | Cayman |
应用文献 |
1.Cain, K.,Inayat-Hussain, S.H.,Couet, C., et al. A cleavage-site-directed inhibitor of interleukin-1β-converting enzyme-like proteases inhibits apoptosis in primary cultures of rat hepatocytes. Biochemistry Journal 314(1), 27-32 (1996). 2.Jacobson, M.D.,Weil, M. and Raff, M.C. Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death. Journal of Cell Biology 133(5), 1041-1051 (1996). 3.Garcia-Calvo, M.,Peterson, E.P.,Leiting, B., et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. The Journal of Biological Chemisty 273, 32608-32613 (1998).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 453.5 |
分子式 | C21H28FN3O7 |
CAS号 | 161401-82-7 |
稳定性 | ≥ 2 years |
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