24α-methyl Cholesterol
货号：
17344-1mg 基本售价：
826.0 元 规格：
1 mg
产品信息
概述| 货号 | 17344-1mg |
| 描述 | 24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism.1 The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques.2 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.3 |
| 别名 | Campesterol;NSC 224330; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Segura, R.,Javierre, C.,Lizarraga, M.A., et al. Other relevant components of nuts: Phytosterols, folate and minerals. British Journal of Nutrition 96(Suppl 2), S36-S44 (2006).
2.Mannarino, E.,Pirro, M.,Cortese, C., et al. Effects of a phytosterol-enriched dairy product on lipids, sterols and 8-isoprostane in hyperchloesterolemic patients: A multicenter Italian study. Nutr.Metab.Cardiovasc.Dis. 19, 84-90 (2009).
3.Chuu, C.P.,Kokontis, J.M.,Hiipakka, R.A., et al. Modulation of liver X receptor signaling as novel therapy for prostate cancer. Journal of Biomedical Science 14, 543-553 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 400.7 |
| 分子式 | C28H48O |
| CAS号 | 474-62-4 |
| 稳定性 | ≥ 2 years |
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