Ac-VEID-AMC
货号:
14989-1mg 基本售价:
826.0 元 规格:
1 mg
产品信息
概述货号 | 14989-1mg |
描述 | Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1 It has also been reported to be cleaved by related proteases, including caspase-8.2 Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. |
别名 | N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-Methylcoumarin;Caspase-6 Substrate (Fluorogenic); |
性能供应商 | Cayman |
应用文献 |
1.Talanian, R.V.,Quinlan, C.,Trautz, S., et al. Substrate specificities of caspase family proteases. The Journal of Biological Chemisty 272, 9677-9682 (1997). 2.Chae, H.J.,Park, K.M.,Lee, G.Y., et al. Je-Chun-Jun induced apoptosis of human cervical carcinoma HeLa cells. Acta Pharmacologica Sinica 25(10), 1372-1379 (2004).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 673.7 |
分子式 | C32H43N5O11 |
CAS号 | 219137-97-0 |
稳定性 | ≥ 2 years |
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