4α-Phorbol 12-myristate 13-acetate
货号：
16806-1mg 基本售价：
825.0 元 规格：
1 mg
产品信息
概述| 货号 | 16806-1mg |
| 描述 | Phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) is a phorbol ester that is commonly used to activate certain types of PKC, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.1 4α-PMA is a structural analog of PMA that does not activate PKC.2,3 It is used as a negative control for PMA signaling through PKC.3 |
| 别名 | 4α-PMA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Blumberg, P.M. Protein kinase C as the receptor for the phorbol ester tumor promoters: Sixth Rhoads Memorial Award Lecture. Cancer Research 48, 1-8 (1988).
2.Fischer, S.M.,Patrick, K.E.,Lee, M.L., et al. 4β- and 4α-12-O-tetradecanoylphorbol-13-acetate elicit arachidonate release from epidermal cells through different mechanisms. Cancer Research 51(3), 850-856 (1991).
3.Savage, M.J.,Trusko, S.P.,Howland, D.S., et al. Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester. Journal of Neuroscience 18(5), 1743-1752 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 616.8 |
| 分子式 | C36H56O8 |
| CAS号 | 63597-44-4 |
| 稳定性 | ≥ 2 years |
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