Patulin
货号：
11346-5mg 基本售价：
812.0 元 规格：
5 mg
产品信息
概述| 货号 | 11346-5mg |
| 描述 | Patulin is a mycotoxin produced by a variety of molds commonly found in rotting apples, including AspergillusandPenicillium.1 Patulin-induced nephropathy and gastrointestinal tract malfunction have been demonstrated in several animal models.2 The oral LD50 value of patulin ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry.1 The World Health Organization considers patulin cytotoxic and established a safety level of patulin in apple juice at 50 μM.2 At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells.2 In 1944, this compound was tested in a clinical trial for potential antibiotic properties to treat the common cold.3 |
| 别名 | Clairformin;Expansin;Mycoin C;NSC 8120;NSC 32951;Penicidin;Terinin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Puel, O.,Galtier, P., and Oswald, I.P. Biosynthesis and toxicological effects of patulin. Toxins 2(4), 613-631 (2010).
2.Liu, B.H.,Wu, T.S.,Yu, F.Y., et al. Induction of oxidative stress response by the mycotoxin patulin in mammalian cells. Toxicological Sciences 95(2), 340-347 (2007).
3.Chalmers, I., and Clarke, M. Commentary: The 1994 patulin trial: The first properly controlled multicentre trial conducted under the aegis of the British Medical Research Council. Int.J.Epidemiol. 32, 253-260 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 154.1 |
| 分子式 | C7H6O4 |
| CAS号 | 149-29-1 |
| 稳定性 | ≥ 2 years |
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