LY294002
货号：
9901S 基本售价：
782.0 元 规格：
1.5mg
产品信息
性能| 供应商 | CST |
| 背景 | LY294002 (PI3 Kinase Inhibitor) was shown to act in vivo as a highly selective inhibitor of phosphatidylinositol 3 (PI3) kinase. When used at a concentration of 50 μM, it specifically abolished PI3 kinase activity (IC50=0.43 μg/ml; 1.40 μM) but did not inhibit other lipid and protein kinases such as PI4 kinase, PKC, MAP kinase or c-Src (1). LY294002 is soluble in DMSO or ethanol. For use with in vitro or cell-based assays, it may be diluted into aqueous buffers to yield the desired concentrations. For experiments with cultured cells, CST recommends treating the cells with LY294002 for one hour prior to, and for the duration of, the stimulation. LY294002 has been shown to block PI3 kinase-dependent Akt phosphorylation and kinase activity. |
| 存放说明 | -20C |
| 参考文献 | Vlahos, C. (1994) J. Biol. Chem. 269, 5241-5248.
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参考图片 |
Molecular Formula: C19H17NO3。 |
