nNOS Inhibitor I
货号：
20906-500ug 基本售价：
770.0 元 规格：
500 ug
产品信息
概述| 货号 | 20906-500ug |
| 描述 | nNOS inhibitor I is a cell-permeable, selective inhibitor of nNOS (Ki = 120 nM).1 It displays >2,500-fold and 320-fold selectivity over eNOS and iNOS, respectively.1 It has been used in a rabbit model for cerebral palsy to prevent hypoxia-ischemia-induced death and to reduce the number of newborn kits exhibiting signs of cerebral palsy.2 |
| 别名 | Neuronal Nitric Oxide Synthase;NOS I;ncNOS; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hah, J.-M.,Roman, L.J.,Martásek, P., et al. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase. J. Med. Chem. 44(16), 2667-2670 (2001).
2.Ji, H.,Tan, S.,Igarashi, J., et al. Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy. Ann. Neurol. 65(2), 209-217 (2009).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 589.4 |
| 分子式 | C8H21N7O2 • 3CF3COOH |
| CAS号 | 357965-99-2 |
| 稳定性 | ≥ 2 years |
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