| 货号 | 20852-5g |
| 描述 | Actarit is an orally active immunomodulator that reduces symptoms in animal models and clinical trials of rheumatoid arthritis.1,2,3 It suppresses inflammation and nitric oxide production, particularly in early stages of disease development.1,2,4 Actarit also alters immunological signaling and symptoms in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.5 |
| 别名 | MS-932;NSC 170317; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Fujisawa, H.,Nishimura, T.,Inogue, Y., et al. Antiinflammatory properties of the new antirheumatic agent 4-acetylaminophenylacetic acid. Arzneimittel-Forschung 40(6), 693-697 (1990). 2.Fujisawa, H.,Nishimura, T.,Motonaga, A., et al. Effect of actarit on type II collagen-induced arthritis in mice. Arzneimittel-Forschung 44(1), 64-68 (1994). 3.Nakamura, H.,Ueki, Y.,Sakito, S., et al. Clinical effects of actarit in rheumatoid arthritis: improvement of early disease activity mediated by reduction of serum concentrations of nitric oxide. Clin. Exp. Rheumatol. 18(4), 445-450 (2000). 4.Alavian, S.M. and Rezaee-Zavareh, M.S. Daclatasvir-based treatment regimens for hepatitis C virus infection: A systematic review and meta-analysis. Hepat. Mon. 16(9), e41077 (2016). 5.Kawai, K.,Kobayashi, Y.,Hirayama, M., et al. Suppressive effects of 4-acetylaminophenylacetic acid (actarit) on experimental autoimmune encephalomyelitis in rats. Immunopharmacol. 39(2), 127-138 (1998). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 193.2 |
| 分子式 | C10H11NO3 |
| CAS号 | 18699-02-0 |
| 稳定性 | ≥ 2 years |
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