Pheophorbide a
货号:
16072-25mg 基本售价:
770.0 元 规格:
25 mg
产品信息
概述货号 | 16072-25mg |
描述 | Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer.1 It has been reported to inhibit U87MG cells with an IC50 value of 2.8 µg/ml and demonstrates cytostatic activity specifically against glioblastoma cells without affecting normal cells.2 It also displays antiproliferative activity against melanoma, breast, and lung cancer cells in vitro at 100 µg/ml.3 |
别名 | 2-Deacetyl-2-vinylbacteriopheophorbide; |
性能供应商 | Cayman |
应用文献 |
1.Cui, B.C.,Yoon, I.,Li, J.Z., et al. Synthesis and characterization of novel purpurinimides as photosensitizers for photodynamic therapy. International Journal of Molecular Sciences 15(5), 8091-8105 (2014). 2.Cho, M.,Park, G.M.,Kim, S.N., et al. Glioblastoma-specific anticancer activity of pheophorbide a from the edible red seaweed Grateloupia elliptica. Journal of Microbiology and Biotechnology 24(3), 346-353 (2014). 3.Baudelet, P.H.,Gagez, A.L.,Bérard, J.B., et al. Antiproliferative activity of Cyanophora paradoxa pigments in melanoma, breast and lung cancer cells. Mar.Drugs 11(11), 4390-4406 (2013).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥90% (mixture of diastereomers) |
计算分子量 | 592.7 |
分子式 | C35H36N4O5 |
CAS号 | 15664-29-6 |
稳定性 | ≥ 2 years |
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