| 货号 | 15991-5mg |
| 描述 | Dibutyryl-cyclic GMP (dibutyryl-cGMP) is a cell-permeable, cGMP analog that activates cGMP-dependent protein kinase.1 It has been used in a wide variety of research applications to mimic cGMP interactions and effects on different biological molecules.2,3,4,5 |
| 别名 | Dibutyryl-cGMP;Dibutyryl Guanosine 3’,5’-cyclic monophosphate; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Cataldi, M.,Secondo, A.,DAlessio, A., et al. Involvement of phosphodiesterase-cGMP-PKG pathway in intracellular Ca2+ oscillations in pituitary GH3 cells. Biochim.Biophys.Acta. 1449(2), 186-193 (1999). 2.Willmott, N.J.,Asselin, J. and Galione, A. Calcium store depletion potentiates a phosphodiesterase inhibitor- and dibutyryl cGMP-evoked calcium influx in rat pituitary GH3 cells. FEBS Letters 386(1), 39-42 (1996). 3.Kaplan, S.S.,Billiar, T.,Curran, R.D., et al. Inhibition of chemotaxis with NG-monomethyl-L-arginine: A role for cyclic GMP. Blood 74(6), 1885-1887 (1989). 4.Chik, C.L.,Liu, Q.Y.,Li, B., et al. cGMP inhibits L-type Ca2+ channel currents through protein phosphorylation in rat pinealocytes. Journal of Neuroscience 15(4), 3104-3109 (1995). 5.Rooney, T.A.,Joseph, S.K.,Queen, C., et al. Cyclic GMP induces oscillatory calcium signals in rat hepatocytes. The Journal of Biological Chemisty 271(33), 19817-19825 (1996). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 507.4 |
| 分子式 | C18H23N5O9P • Na |
| CAS号 | 51116-00-8 |
| 稳定性 | ≥ 2 years |
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