1,2-Dioleoyl-sn-glycero-3-PE
货号：
15091-100mg 基本售价：
756.0 元 规格：
100 mg
产品信息
概述| 货号 | 15091-100mg |
| 描述 | 1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.1,2,3 |
| 别名 | 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine;1,2-DOPE; |
性能| 供应商 | Cayman |
| 应用文献 |
1.MacDonald, R.C.,Rakhmanova, V.A.,Choi, K.L., et al. O-ethylphosphatidylcholine: A metabolizable cationic phospholipid which is a serum-compatible DNA transfection agent. Journal of Pharmaceutical Sciences 88(9), 896-904 (1999).
2.Misra, S.K.,Biswas, J.,Kondaiah, P., et al. Gene transfection in high serum levels: Case studies with new cholesterol based cationic gemini lipids. PLoS One 8(7), e68305 (2013).
3.Chen, Y.,Sun, J.,Lu, Y., et al. Complexes containing cationic and anionic pH-sensitive liposomes: Comparative study of factors influencing plasmid DNA gene delivery to tumors. Int.J.Nanomedicine 8, 1573-1593 (2013).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 744.1 |
| 分子式 | C41H78NO8P |
| CAS号 | 768593 |
| 稳定性 | ≥ 2 years |
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