Wogonin
货号：
14248-5mg 基本售价：
735.0 元 规格：
5 mg
产品信息
概述| 货号 | 14248-5mg |
| 描述 | Wogonin is an O-methylated flavonoid isolated from the root of the traditional Chinese herb S. baicalensis with anti-inflammatory, antioxidant, and neuroprotective activities.1 At concentrations of 5-50 μM, wogonin inhibits inflammatory activation of cultured brain microglia by diminishing LPS-induced TNF-α, IL-1β, and nitric oxide production.2 Wogonin at 75 μM demonstrates tumor therapeutic potential inducing sub-G1 phase apoptosis through activation of caspase-3 activity in human osteocarcinoma cell lines.3 |
| 别名 | BRN 0287152; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Huang, W.H.,Chien, P.Y.,Yang, C.H., et al. Novel synthesis of flavonoids of Scutellaria baicalensis GEORGI. Chemical & Pharmaceutical Bulletin 51(3), 339-340 (2003).
2.Lee, H.,Kim, Y.O.,Kim, H., et al. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. The FASEB Journal 17(13), 1943-1944 (2003).
3.Lin, C.C.,Kuo, C.L.,Lee, M.H., et al. Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. International Journal of Oncology 39(1), 217-224 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 284.3 |
| 分子式 | C16H12O5 |
| CAS号 | 632-85-9 |
| 稳定性 | ≥ 2 years |
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