货号 | 4749/50 |
供应商 | Tocris |
生物活性 | Calcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 158.53 |
分子式 | SrCl2 |
可溶性/溶解性 | Soluble to 100 mM in water |
参考文献 | Thomsenet al (2012) Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells. J.Pharmacol.Exp.Ther. 343 638. PMID: 22942242. Yanget al (2011) Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling. Stem Cells 29 981. PMID: 21563277. |