| 货号 | 4121/50 |
| 别名 | 3-[[(4-Methyl-1-piperazinyl)imino]m |
| 供应商 | Tocris |
| 生物活性 | Antibiotic; inhibits bacterial RNA polymerase. Prototypical activator of the pregnane X receptor (PXR). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 822.94 |
| 分子式 | C43H58N4O12< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Huet al (2010) Pregnane X receptor is SUMOylated to repress the inflammatory response. J.Pharmacol.Exp.Ther. 335 342. PMID: 20719936. Artsimovitchet al (2005) Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell 122 351. PMID: 16096056. Mooreet al (2000) Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J.Biol.Chem. 275 15122. PMID: 10748001. Wehrli (1983) Rifampin: mechanisms of action and resistance. Rev.Infect.Dis. 5 S407. PMID: 6356275. |