| 货号 | 3109/50 |
| 别名 | 5-(Aminosulfonyl)-4-chloro-2-([2-fu |
| 供应商 | Tocris |
| 生物活性 | Loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) symporter. Also acts as a non-competitive antagonist at GABAA receptors with ~ 100-fold greater selectivity for α6-containing receptors than α1-containing receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 330.74 |
| 分子式 | C12H11ClN2O5S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 54-31-9 |
| 参考文献 | Gutschmidtet al (1999) Anticonvulsant actions of furosemide in vitro. Neuroscience 91 1471. PMID: 10391452. Thompsonet al (1999) Residues in transmembrane domains I and II determine γ-aminobutyric acid type AA receptor subtype-selective antagonism by furosemide. Mol.Pharmacol. 55 993. PMID: 10347239. |