| 货号 | 4094/50 |
| 别名 | 2-Methyl-N-(4-nitro-3-[trifluoromet |
| 供应商 | Tocris |
| 生物活性 | Non-steroidal antiandrogen; competitive antagonist of the androgen receptor. Blocks the biological activity of testosterone (Cat. No. 2822) in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 276.21 |
| 分子式 | C11H11F3N2O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 13311-84-7 |
| 参考文献 | Fosteret al (2011) Drug safety is a barrier to the discovery and development of new androgen receptor antagonists. Prostate 71 480. PMID: 20878947. Butcheret al (2007) Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. Cancer Res. 67 85. PMID: 17210686. Sufrin and Coffey (1976) Flutamide. Mechanism of action of a new nonsteroidal antiandrogen. Invest.Urol. 13 429. PMID: 1270239. |