| 货号 | 4090/50 |
| 别名 | (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethyl |
| 供应商 | Tocris |
| 生物活性 | Broad-spectrum antibiotic and MMP inhibitor; tetracycline derivative. Increases and promotes smooth muscle cell adhesion; inhibits proliferation and migration. Protects the microvasculature by inhibiting plasminogen systems. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 512.94 |
| 分子式 | C22H24N2O8稨Cl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 24390-14-5 |
| 参考文献 | Werniget al (2008) A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat.Biotechnol. 26 916. PMID: 18594521. Burggrafet al (2007) Doxycycline inhibits MMPs via modulation of plasminogen activators in focal cerebral ischemia. Neurobiol.Dis. 25 506. PMID: 17166729. Francoet al (2006) Doxycycline alters vascular smooth muscle cell adhesion, migration, and reorganization of fibrillar collagen matrices. Am.J.Pathol. 168 1697. PMID: 16651635. |