| 货号 | 4202/50 |
| 别名 | 6-Aminopurine hydrochloride |
| 供应商 | Tocris |
| 生物活性 | High affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). Inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor; also stimulates GTPγS binding (pEC50 values are 8.54 and 7.21 respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 171.59 |
| 分子式 | C5H5N5.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Gorzalkaet al (2005) Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues. Mol.Pharmacol. 67 955. PMID: 15604413. Benderet al (2002) Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule. Proc.Natl.Acad.Sci. 998573. |