9-Deazaguanine
货号：
21674-5mg 基本售价：
686.0 元 规格：
5 mg
产品信息
概述| 货号 | 21674-5mg |
| 描述 | 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).1 Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection.2 |
| 别名 | NSC 344522; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wielgus-Kutrowska, B.,Breer, K.,Hashimoto, M., et al. Trimeric purine nucleoside phosphorylase: Exploring postulated one-third-of-the-sites binding in the transition state. Bioorg. Med. Chem. 20(22), 6758-6769 (2012).
2.Schramm, V.L. Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents. Biochim Biophys. Acta. 1587(2-3), 107-117 (2002).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 150.1 |
| 分子式 | C6H6N4O |
| CAS号 | 65996-58-9 |
| 稳定性 | ≥ 2 years |
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