Omeprazole sulfide
货号:
18885-100mg 基本售价:
686.0 元 规格:
100 mg
产品信息
概述货号 | 18885-100mg |
描述 | Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole (Item No. 14880) and esomeprazole (Item No. 17326).1 As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 µM).2 |
别名 | Pyrmetazole;Ufiprazole; |
性能供应商 | Cayman |
应用文献 |
1.Olbe, L.,Carlsson, E., and Lindberg, P. A proton-pump inhibitor expedition: The case histories of omeprazole and esomeprazole. Nature Reviews.Drug Discovery 2(2), 132-139 (2003). 2.Ogilvie, B.W.,Yerino, P.,Kazmi, F., et al. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: Implications for coadministration with clopidogrel. Drug Metabolism and Disposition 39(11), 2020-2033 (2011).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 329.4 |
分子式 | C17H19N3O2S |
CAS号 | 73590-85-9 |
稳定性 | ≥ 2 years |
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