VEGFR Tyrosine Kinase Inhibitor II
货号：
17654-1mg 基本售价：
686.0 元 规格：
1 mg
产品信息
概述| 货号 | 17654-1mg |
| 描述 | VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50s = 20, 180, and 240 nM, respectively).1 It displays minimal activity against c-Src and EGFR (IC50s = 7 and 7.3 µM, respectively) and is inactive against Cdk1, c-Met, IGF-1R, and PKA (IC50s > 10 µM).1 VEGFR tyrosine kinase inhibitor II has been investigated for its potential to inhibit tumor induced angiogenesis.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Furet, P.,Bold, G.,Hofmann, F., et al. Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searching. Bioorganic & Medicinal Chemistry Letters 13(18), 2967-2971 (2003).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 337.8 |
| 分子式 | C19H16ClN3O |
| CAS号 | 269390-69-4 |
| 稳定性 | ≥ 2 years |
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