6-(4-Methoxyphenyl)-3-pyridazinamine
货号：
17588-5mg 基本售价：
686.0 元 规格：
5 mg
产品信息
概述| 货号 | 17588-5mg |
| 描述 | Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs.1 6-(4-Methoxyphenyl)-3-pyridazinamine is an aminopyridazine derivative that acts as a GABAA receptor antagonist.2 It can also be used as an intermediate in the synthesis of SR 95531 (Item No. 14585).2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Karobath, M., and Sperk, G. Stimulation of benzodiazepine receptor binding by γ-aminobutyric acid. Proceedings of the National Academy of Sciences of the United States of America 76(2), 1004-1006 (1979).
2.Wermuth, C.G.,Bourguignon, J.J.,Schlewer, G., et al. Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of γ-aminobutyric acid acting as selective GABA-A antagonists. Journal of Medicinal Chemistry 30(2), 239-249 (1987).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 201.2 |
| 分子式 | C11H11N3O |
| CAS号 | 4776-87-8 |
| 稳定性 | ≥ 2 years |
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