| 货号 | 16347-1mg |
| 描述 | 3-deoxy Glucosone is a highly reactive 2-oxoaldehyde intermediate of the Maillard reaction produced during oxidative stress in response to excess sugar consumption and in association with diabetes.1,2,3 It is a precursor for the formation of advanced glycation endproducts and because it readily reacts with protein amino groups is also used for crosslinking studies.4 3-deoxy Glucosone can be used as a reference for the analysis and detection of glucose degradation products and glycating agents. |
| 别名 | 2-keto-3-Deoxyglucose;3-deoxy-D-erythro-Hexosulose; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Yamada, H.,Miyata, S.,Igaki, N., et al. Increase in 3-deoxyglucosone levels in diabetic rat plasma. Specific in vivo determination of intermediate in advanced Maillard reaction. The Journal of Biological Chemisty 269(32), 20275-20280 (1994). 2.Kusunoki, H.,Miyata, S.,Ohara, T., et al. Relation between serum 3-deoxyglucosone and development of diabetic microangiopathy. Diabetes Care 26(6), 1889-1894 (2003). 3.Niwa, T. and Tsukushi, S. 3-Deoxyglucosone and AGEs in uremic complications: Inactivation of glutathione peroxidase by 3-deoxyglucosone. Kidney Int.Suppl. 78, S37-S41 (2001). 4.Thornalley, P.J.,Langborg, A. and Minhas, H.S. Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose. Biochemistry Journal 344(Pt 1), 109-116 (1999). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 162.1 |
| 分子式 | C6H10O5 |
| CAS号 | 4084-27-9 |
| 稳定性 | ≥ 2 years |
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