| 货号 | 15908-5mg |
| 描述 | Paroxetine (Item No. 14998) is a potent, selective serotonin reuptake inhibitor (Ki = 0.72 nM) that has been used in cases of depression and anxiety disorder.1,2,3 Desmethylene paroxetine is a major urinary metabolite of paroxetine.4,5 This compound may be used in urine drug testing applications involving paroxetine toxicology or forensic analysis. |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Mattson, R.J.,Catt, J.D.,Denhart, D.J., et al. Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors. Journal of Medicinal Chemistry 48(19), 6023-6034 (2005). 2.Baldwin, D.,Woods, R.,Lawson, R., et al. Efficacy of drug treatments for generalised anxiety disorder: Systematic review and meta-analysis. BMJ 342, d1199 (2011). 3.Ackermann, R.T. and Williams, J.W., Jr. Rational treatment choices for non-major depressions in primary care. J.Gen.Intern.Med. 17(4), 293-301 (2002). 4.Segura, M.,Roura, L.,de La Torre, R., et al. Synthesis of the major metabolites of paroxetine. Bioorganic Chemistry 31(3), 248-258 (2003). 5.Wei, P.,Kaatz, G.W. and Kerns, R.J. Structural differences between paroxetine and femoxetine responsible for differential inhibition of Staphylococcus aureus efflux pumps. Bioorganic & Medicinal Chemistry Letters 14(12), 3093-3097 (2004). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 353.8 |
| 分子式 | C18H20FNO3 • HCl |
| CAS号 | 1394861-12-1 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |