Minoxidil
货号：
15302-100mg 基本售价：
686.0 元 规格：
100 mg
产品信息
概述| 货号 | 15302-100mg |
| 描述 | Minoxidil is a pyrimidine derivative that was originally developed as an anti-hypertensive agent and unexpectedly found to stimulate hair growth. Minoxidil directly affects arteriolar smooth muscle to decrease vascular resistance in part by opening ATP-sensitive potassium channels.1,2 It can activate cyclooxygenase 1 (AC50 = 80 μM), which is expressed in the dermal papilla of hair follicles, increasing prostaglandin E2 production in BALB/c 3T3 fibroblasts and human dermal papilla fibroblasts.3 |
| 别名 | Loniten;U-10858; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Limas, C.J. and Cohn, J.N. Stimulation of vascular smooth muscle sodium, potassium--adenosinetriphosphatase by vasodilators. Circulation Research 35(4), 601-607 (1974).
2.Imenshahidi, M.,Hadizadeh, F.,Firoozeh-Moghadam, A., et al. Synthesis and vasorelaxant effect of 9-aryl-1,8-acridinediones as potassium channel openers in isolated rat aorta. Iran.J.Pharm.Res. 11(1), 229-233 (2012).
3.Michelet, J.F.,Commo, S.,Billoni, N., et al. Activation of cytoprotective prostaglandin synthase-1 by minoxidil as a possible explanation for its hair growth-stimulating effect. Journal of Investigative Dermatology 108, 205-209 (1997).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 209.3 |
| 分子式 | C9H15N5O |
| CAS号 | 38304-91-5 |
| 稳定性 | ≥ 2 years |
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