| 货号 | 15006-25mg |
| 描述 | Clindamycin is an antibiotic in the lincosamide class which binds the bacterial 50S ribosomal subunit and interferes with protein synthesis.1,2 Evidence suggests that clindamycin is particularly effective against anaerobes and is commonly used against Gram positive bacteria.1,2,3 It is used for serious infections and in the prevention of emerging infections in burns.4,5,3,6 Clindamycin is also effective against P. falciparum and is used as an antimalarial, either alone or in combination therapy.7 |
| 别名 | U 21251; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kouvela, E.C.,Petropoulos, A.D. and Kalpaxis, D.L. Unraveling new features of clindamycin interaction with functional ribosomes and dependence of the drug potency on polyamines. The Journal of Biological Chemisty 281(32), 23103-23110 (2006). 2.Rasmussen, B.A.,Bush, K. and Tally, F.P. Antimicrobial resistance in anaerobes. Clinical Infectious Diseases 24, S110-S120 (1997). 3.Frankel, R.I. Clindamycin - efficacy and toxicity. West J.Med. 122(6), 526-530 (1975). 4.Verstraelen, H.,Verhelst, R.,Roelens, K., et al. Antiseptics and disinfectants for the treatment of bacterial vaginosis: A systematic review. BMC Infect.Dis. 12(148), (2012). 5.Dryden, M.S. Complicated skin and soft tissue infection. J. Antimicrob. Chemother. 65(Suppl 3), iii35-iii44 (2010). 6.Branski, L.K.,Al-Mousawi, A.,Rivero, H., et al. Emerging infections in burns. Surg.Infect. 10(5), 389-397 (2009). 7.Lell, B. and Kremsner, P.G. Clindamycin as an antimalarial drug: Review of clinical trials. Antimicrobial Agents and Chemotherapy 46(8), 2315-2320 (2002). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 425 |
| 分子式 | C18H33ClN2O5S |
| CAS号 | 18323-44-9 |
| 稳定性 | ≥ 2 years |
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