MDL 12330A (hydrochloride)
货号：
14559-5mg 基本售价：
686.0 元 规格：
5 mg
产品信息
概述| 货号 | 14559-5mg |
| 描述 | MDL 12330A is an adenylyl cyclase inhibitor that can also inhibit cAMP and cGMP phosphodiesterases and block slow extracellular and store-operated Ca2+ entry into cells. It is widely used to investigate the role of the adenylyl cyclase/cAMP signaling pathway. MDL 12330A has also been reported to block voltage-dependent K+ channels, extend action potential duration, and enhance insulin secretion in pancreatic β-cells.1 |
| 别名 | RMI 12330A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Li, X.,Guo, Q.,Gao, J., et al. The adenylyl cyclase inhibitor MDL-12,330A potentiates insulin secretion via blockade of voltage-dependent K+ channels in pancreatic beta cells. PLoS One 8(10), e77934 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 377 |
| 分子式 | C23H36N2 • HCl |
| CAS号 | 40297-09-4 |
| 稳定性 | ≥ 2 years |
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