diacetoxy Scirpenol
货号：
11427-1mg 基本售价：
686.0 元 规格：
1 mg
产品信息
概述| 货号 | 11427-1mg |
| 描述 | diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases.1 It is toxic to fungi, plants, animals, and various mammalian cell cultures, inhibiting de novo protein synthesis.2 In a biological activity assay, DAS was shown to inhibit expression of the Arabidopsis MAMP-responsive reporter gene WRKY29p::GUS with an IC50 value of 50 nM, thereby suppressing a rapid cell death immune response important for plant defense.3 |
| 别名 | Anguidin;DAS;NSC 141537;NSC 177378;Scirpenetriol 4,15-diacetate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bauer, J.,Bollwahn, W.,Gareis, M., et al. Kinetic profiles of diacetoxyscirpenol and two of its metabolites in blood serum of pigs. Applied and Environmental Microbiology 49(4), 842-845 (1985).
2.Shams, M.,Mitterbauer, R.,Corradini, R., et al. Isolation and characterization of a new less-toxic derivative of the Fusarium mycotoxin diacetoxyscirpenol after thermal treatment. Journal of Agricultural and Food Chemistry 59, 9709-9714 (2011).
3.Serrano, M.,Hubert, D.A.,Dangl, J.L., et al. A chemical screen for suppressors of the avrRpm1-RPM1-dependent hypersensitive cell death response in Arabidopsis thaliana. Planta. 231, 1013-1023 (2010).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 366.4 |
| 分子式 | C19H26O7 |
| CAS号 | 2270-40-8 |
| 稳定性 | ≥ 2 years |
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