| 货号 | 4055/50 |
| 别名 | 3-Oxo-L-gulofuranolactone |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of Cav3.2 channels (IC50 = 6.5 μM); displays no effect on Cav3.1 or Cav3.3 channels heterologously expressed in HEK 293 cells. Also enhances the generation of induced pluripotent stem cells (iPSCs) from mouse and human somatic cells by increasing reprogramming efficiency. Naturally occurring antioxidant. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 176.12 |
| 分子式 | C6H8O6 |
| 可溶性/溶解性 | Soluble to 500 mM in water and to 100 mM in DMSO |
| CAS号 | 50-81-7 |
| 参考文献 | Estebanet al (2010) Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 6 71. PMID: 20036631. Nelsonet al (2007) Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J.Neurosci. 27 12577. PMID: 18003836. Padayattyet al (2003) Vitamin C as an antioxidant: evaluation of its role in disease prevention. J.Am.Coll.Nutr. 22 18. PMID: 12569111. |