| 货号 | 4111/50 |
| 别名 | N,N,N,N',N',N'-Hexamethylhexamethylene |
| 供应商 | Tocris |
| 生物活性 | Nicotinic receptor (nAChR) blocker at autonomic ganglia; prevents nicotine-mediated inhibition of apoptosis. Induces changes in neuronal activity similar to the influences of glutamate in vitro. Inhibits nicotine-mediated induction of XIAP and survivin. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 362.19 |
| 分子式 | C12H30Br2N2< |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 50 mM in DMSO |
| 参考文献 | Dasguptaet al (2010) Nicotine inhibits apoptosiis induced by chemotherapeutic drugs by up-regulating XIAP and survivin. Proc.Natl.Acad.Sci. 1036332. Karavaevet al (2008) The nicotinic receptor blocker hexamethonium alters neuronal responses to glutamate in the medial septal area of the brain of the ground squirrel in vitro. Neurosci.Behav.Physiol. 38 297. PMID: 18264777. |