| 货号 | 4109/50 |
| 别名 | N4-(7-Chloro-4-quinolinyl)-N1,N1-di |
| 供应商 | Tocris |
| 生物活性 | Antimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine (Cat. No. 3977). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 515.86 |
| 分子式 | C18H26ClN3 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| 参考文献 | Jianget al (2010) Antitumor and antimetastatic activities of chloroquine diphosphate in a murine model of breast cancer. Biomed.Pharmacother. 64 609. PMID: 20888174. Sasakiet al (2010) Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 10 370. PMID: 20630104. |