货号 | 14581-50mg |
描述 | NMDA is a synthetic amino acid derivative that acts as a specific agonist at the NMDA receptor, mimicking the excitatory action of the endogenous ligand glutamate.1,2 Signaling through the NMDA receptor influences both neuronal plasticity and neurotoxicity.3 Repetitive activation of NMDA synapses leads to long-term potentiation, which is used as a model of learning and the initial stages of memory formation.4 |
别名 | N-Methyl-D-Aspartic Acid; |
供应商 | Cayman |
应用文献 | |
1.Ishii, T.,Moriyoshi, K.,Sugihara, H., et al. Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. The Journal of Biological Chemisty 268(4), 2836-2843 (1993). 2.Ferkany, J.W.,Zaczek, R. and Coyle, J.T. Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors. Nature 298(19), 757-759 (1982). 3.Nakanishi, S. Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603 (1992). 4.Izquierdo, I. Role of NMDA receptors in memory. Trends in Pharamacological Sciences 12, 128-129 (1991). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 147.1 |
分子式 | C5H9NO4 |
CAS号 | 6384-92-5 |
稳定性 | ≥ 2 years |
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