货号 | 14174-5mg |
描述 | Genistin is a natural isoflavone isolated from legumes, including soy and kudzu. It is a phytoestrogen, as it stimulates the growth of estrogen-dependent human breast cancer cells in vivo.1 Like other isoflavones, genistin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.2,3 It also increases bone formation in collagen matrix in vivo.4 |
别名 | NSC 5112; |
供应商 | Cayman |
应用文献 | |
1.Allred, C.D.,Ju, Y.H.,Allred, K.F., et al. Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein. Carcinogenesis 22(10), 1667-1673 (2001). 2.Uesugi, T.,Toda, T.,Tsuji, K., et al. Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin. Biological and Pharmaceutical Bullentin 24(4), 368-372 (2001). 3.Li, X.h.,Zhang, J.C.,Sui, S.f., et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. Acta.Pharmacol.Sin. 26(9), 1081-1086 (2005). 4.Wong, R.W. and Rabie, A.B. Effect of genistin on bone formation. Front.Biosci.(Elite Ed.) 2, 764-770 (2010). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 432.4 |
分子式 | C21H20O10 |
CAS号 | 529-59-9 |
稳定性 | ≥ 2 years |
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