Pyroxamide
货号:
13870-5mg 基本售价:
672.0 元 规格:
5 mg
产品信息
概述货号 | 13870-5mg |
描述 | Pyroxamide is an inhibitor of histone deacetylases (HDACs), including HDAC1 (IC50 = 0.1-0.2 μM).1,2 It induces growth suppression and cell death of certain types of cancer cells in culture.3,1 |
性能供应商 | Cayman |
应用文献 |
1.Butler, L.M.,Webb, Y.,Agus, D.B., et al. Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase. Clinical Cancer Research 7, 962-970 (2001). 2.Remiszewski, S.W.,Sambucetti, L.C.,Atadja, P., et al. Inhibitors of human histone deacetylase: Synthesis and enzyme and cellular activity of straight chain hydroxamates. Journal of Medicinal Chemistry 45(4), 753-757 (2002). 3.Kutko, M.C.,Glick, R.D.,Butler, L.M., et al. Histone deacetylase inhibitors induce growth suppression and cell death in human rhabdomyosarcoma in vitro. Clinical Cancer Research 9, 5749-5755 (2003).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 265.3 |
分子式 | C13H19N3O3 |
CAS号 | 382180-17-8 |
稳定性 | ≥ 2 years |
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