Ochratoxin A
货号：
11439-1mg 基本售价：
672.0 元 规格：
1 mg
产品信息
概述| 货号 | 11439-1mg |
| 描述 | Ochratoxin A (OTA) is a mycotoxin produced by A. ochraceus,A. carbonarius, and P. verrucosum that is commonly found as a food contaminant.1 The kidney is the main target organ for OTA toxicity where it has been reported to trigger nephropathy and induce renal adenomas.2 Topical OTA exposure (80 μg/mouse) also has skin tumor initiating properties which have been linked to oxidative stress, alterations in Nrf2 and MAPK signaling, and DNA damage.3 A tolerable weekly intake of 100 ng/kg body weight per day has been set by the joint FAO/WHO Expert Committee on Food Additives.2 |
| 别名 | NSC 201422;NSC 221991;OTA; |
| 是否危险品 | 是 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Health, U.S.D.o., and Human, S. Ochratoxin A: CAS No. 303-47-9. Report on Carcinogens, Twelfth Edition 12, 335-337 (2011).
2.Marin-Kuan, M.,Ehrlich, V.,Delatour, T., et al. Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin A. J.Toxicol. 2011, (2011).
3.Kumar, R.,Ansari, K.M.,Chaudhari, B.P., et al. Topical application of ochratoxin A causes DNA damage and tumor initiation in mouse skin. PLoS One 7(10), (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥90% |
| 计算分子量 | 403.8 |
| 分子式 | C20H18ClNO6 |
| CAS号 | 303-47-9 |
| 稳定性 | ≥ 2 years |
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