Picotamide
货号：
21690-5mg 基本售价：
644.0 元 规格：
5 mg
产品信息
概述| 货号 | 21690-5mg |
| 描述 | Picotamide is an antiplatelet drug that inhibits both thromboxane A2(TXA2) receptors (Kd = 325 nM) and TXA2synthase.1,2 It significantly inhibits basal and lipopolysaccharide-stimulated TXA2 synthesis by rat peritoneal macrophages when used at 0.5 mM.3 Formulations containing picotamide have potential applications in the reduction of peripheral artery disease in patients with diabetes.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Celestini, A. and Violi, F. A review of picotamide in the reduction of cardiovascular events in diabetic patients. Vasc. Health Risk Manag. 3(1), 93-98 (2008).
2.Modesti, P.A.,Cecioni, I.,Colella, A., et al. Binding kinetics and antiplatelet activities of picotamide, a thromboxane A2 receptor antagonist. Br. J. Pharmacol. 112(1), 81-86 (1994).
3.Matera, G.,Chisari, M.,Altavilla, D., et al. Selective thromboxane synthetase inhibition by picotamide and effects on endotoxin-induced lethality. Proc. Soc. Exp. Biol. Med. 187(1), 58-61 (1988).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 376.4 |
| 分子式 | C21H20N4O3 |
| CAS号 | 32828-81-2 |
| 稳定性 | ≥ 1 year |
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