Ac-Calpastatin (184-210)
货号：
16501-100ug 基本售价：
644.0 元 规格：
100 ug
产品信息
概述| 货号 | 16501-100ug |
| 描述 | The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium.1 Ac-calpastatin (184-210) is an acetylated synthetic peptide from human calpastatin that strongly inhibits both calpains I and II but not papain (a cysteine protease) or trypsin (a serine protease).2 This 27 amino acid peptide is encoded by exon 1B of Ac-calpastatin (184-210) and corresponds to a portion of inhibitory domain 1.2,3 |
| 别名 | Calpastatin Peptide B27-WT; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Goll, D.E.,Thompson, V.F.,Li, H., et al. The calpain system. Physiological Reviews 83(3), 731-801 (2003).
2.Maki, M.,Bagci, H.,Hamaguchi, K., et al. Inhibition of calpain by synthetic oligopeptide corresponding to an exon of the human calpastatin gene. The Journal of Biological Chemisty 264(32), 18866-18869 (1999).
3.Betts, R.,Weinsheimer, S.,Blouse, G.E., et al. Structural determinants of the calpain inhibitory activity of calpastatin peptide B27-WT. The Journal of Biological Chemisty 278(10), 7800-7809 (2003).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 3177.7 |
| 分子式 | C142H230N36O44S |
| CAS号 | 79079-11-1 |
| 稳定性 | ≥ 2 years |
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