RG-13022
货号：
10010309-5mg 基本售价：
644.0 元 规格：
5 mg
产品信息
概述| 货号 | 10010309-5mg |
| 描述 | Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation.1 RG-13022 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 1 µM in HT-22 cells.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gazit, A.,Yaish, P.,Gilon, C., et al. Tyrphostins I: Synthesis and biological activity of protein tyrosine kinase inhibitors. Journal of Medicinal Chemistry 32(10), 2344-2352 (1989).
2.Sagara, Y.,Ishige, K.,Tsai, C., et al. Tyrphostins protect neuronal cells from oxidative stress. The Journal of Biological Chemisty 277(39), 36204-36215 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 266.3 |
| 分子式 | C16H14N2O2 |
| CAS号 | 149286-90-8 |
| 稳定性 | ≥ 2 years |
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