| 货号 | 9886S |
| 供应商 | CST |
| 背景 | Docetaxel belongs to the taxane family of antitumor and antileukemic agents (1). A microtubule-stabilizing agent, docetaxel acts as an inhibitor of cellular functions that require microtubule dynamics including cell division, and is now in use as a treatment for breast, prostate and lung cancer (2).多烯紫杉醇属于抗肿瘤和抗白血病药物的紫杉醇家族(1)。作为一种微管稳定药物，多烯紫杉醇能够充当需要微管动力学如细胞分裂的抑制剂，现在用于乳腺癌、前列腺癌和肺癌的治疗(2)。 |
| 存放说明 | -20C |
| 参考文献 | Abal, M. et al. (2003) Curr Cancer Drug Targets 3, 193-203. Crown, J. and OLeary, M. (2000) Lancet 355, 1176-8. |
Western blot analysis of extracts from HT-29 cells treated with Docetaxel (100 ng/ml) for the indicated times using Cyclin B1 Antibody #4138 (upper) or Phospho-Aurora A (Thr288) (C39D8) Rabbit mAb #3079 (lower).Western blot 方法检测Docetaxel (100 ng/ml)处理不同时间的HT-29细胞提取物，检测抗体为Cyclin B1 Antibody #4138 (上图) 或 Phospho-Aurora A (Thr288) (C39D8) Rabbit mAb #3079 (下图). | |
Structure of Docetaxel Docetaxel的结构。 |
