| 货号 | 21891-500ug |
| 描述 | Taurocholic acid-d4 is intended for use as an internal standard for the quantification of taurocholic acid (Item No. 16215) by GC- or LC-MS. Taurocholic acid is a bile salt formed in the liver by conjugation of cholic acid with taurine that is involved in the emulsification of lipids.1 It can be used to solubilize lipids and membrane-bound proteins.2,3,4 |
| 别名 | Ethanesulfonic Acid-d4; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Beuers, U. Effects of bile acids on hepatocellular signaling and secretion. Yale Journal of Biology and Medicine 70(4), 341-346 (1997). 2.Loe, D.W.,Almquist, K.C.,Cole, S.P., et al. ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. The Journal of Biological Chemisty 271(16), 9683-9689 (1996). 3.Craddock, A.L.,Love, M.W.,Daniel, R.W., et al. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. American Journal of Physiology 274(1.1), G157-G169 (1998). 4.Kim, R.B.,Leake, B.,Cvetkovic, M., et al. Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. Journal of Pharmacology and Experimental Therapeutics 291(3), 1204-1209 (1999). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 541.7 |
| 分子式 | C26H40D4NO7S • Na |
| 稳定性 | ≥ 3 years |
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