货号 | 21427-100mg |
描述 | Tosufloxacin is a fluoroquinolone antibiotic. It has activity against diverse aerobic and anaerobic bacteria in vitro.1,2 Tosufloxacin is also effective against bacterial persisters, showing significant activity against S. aureus and uropathogenic E. colipersisters.3,4 As with many other quinolones, tosufloxacin use can be associated with significant side effects.5 |
供应商 | Cayman |
应用文献 | |
1.Espinoza, A.M.,Chin, N.-X.,Novelli, A., et al. Comparative in vitro activity of a new fluorinated 4-quinolone, T-3262 (A-60969). Antimicrob. Agents Chemother. 32(5), 663-670 (1988). 2.Fernandes, P.B.,Chu, D.T.W.,Swanson, R.N., et al. A-61827 (A-60969), a new fluoronaphthyridine with activity against both aerobic and anaerobic bacteria. Antimicrob. Agents Chemother. 32(1), 27-32 (1988). 3.Niu, H.Y.,Cui, P.,Yee, R., et al. A clinical drug library screen identifies tosufloxacin as being highly active against Staphylococcus aureus persisters. Antibiotics (Basel) 4(3), 329-336 (2015). 4.Niu, H.Y.,Cui, P.,Shi, W., et al. Identification of Anti-Persister Activity against Uropathogenic Escherichia coli from a Clinical Drug Library. Antibiotics (Basel) 4(2), 179-187 (2015). 5.Rubinstein, E. History of quinolones and their side effects. Chemotherapy 47 (Suppl. 3), 44-48 (2001). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 576.5 |
分子式 | C19H15F3N4O3 • C7H8O3S |
CAS号 | 115964-29-9 |
稳定性 | ≥ 2 years |
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