| 货号 | 21236-10mg |
| 描述 | Secnidazole is a 5-nitroimidazole derivative with antiparasitic and antibiotic activity.1,2 It exhibits a mean minimum inhibitory concentration of 2.59 µM against 16 clinical isolates of B. fragilis.2 It shows efficacy against ameobiasis, giardiasis, H. pylori and other parasites and microbes.1,3,4,5,6 |
| 别名 | PM 185184;RP 14539; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Nagata, N.,Mariott, D.,Harkenss, J., et al. Current treatment options for Dientamoeba fragilis infections. Int. J. Parasitol. Drugs Drug Resist. 2, 204-215 (2012). 2.Jokipii, L. and Jokipii, A.M.M. Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis group. Antimicrobial Agents and Chemotherapy 28(4), 561-564 (1985). 3.Almirall, P.,Escobedo, A.A.,Ayala, I., et al. Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trial. J. Parasitol. Res. 2011, 636857 (2011). 4.Silva, F.M.,Eisig, J.N.,Chehter, E.Z., et al. Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcer. Rev. Hosp. Clin. Fac. Med. Sao Paulo 57(1), 9-14 (2002). 5.Omrani, G.,Rastegar-Lari, A. and Khamseh, M. Effect of single dose of secnidazole in treatment of intestinal amoebiasis. J. Pak. Med. Assoc. 4596), 159 (1995). 6.De backer, E.,Dubreuil, L.,Brauman, M., et al. In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis. Clin. Microbiol. Infect. 16(5), 470-472 (2010). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 185.2 |
| 分子式 | C7H11N3O3 |
| CAS号 | 3366-95-8 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |