Satraplatin
货号：
20537-1mg 基本售价：
630.0 元 规格：
1 mg
产品信息
概述| 货号 | 20537-1mg |
| 描述 | Satraplatin is an orally available antineoplastic platinum(IV) complex.1 It is more hydrophobic than cisplatin (Item No. 13119) or oxaliplatin (Item No. 13106), which reduces transport-determined acquired resistance.1 Satraplatin also displays less neurotoxicity in rats than cisplatin or tetraplatin.2 Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies.3 |
| 别名 | BMS-182751;BMY 45594;JM 216; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kelland, L.R.,Abel, G.,McKeage, M.J., et al. Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): An orally active platinum drug. Cancer Res. 53(11), 2581-2586 (1993).
2.McKeage, M.J.,Boxall, F.E.,Jones, M., et al. Lack of neurotoxicity of oral bisacetatoamminedichlorocyclohexylamine-platinum(IV) in comparison to cisplatin and tetraplatin in the rat. Cancer Res. 54(3), 629-631 (1994).
3.Bhargava, A. and Vaishampayan, U.N. Satraplatin: Leading the new generation of oral platinum agents. Expert. Opin. Investig. Drugs 18(11), 1787-1797 (2009).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 500.3 |
| 分子式 | C10H22Cl2N2O4Pt |
| CAS号 | 129580-63-8 |
| 稳定性 | ≥ 2 years |
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