Hesperidin
货号：
18646-50g 基本售价：
630.0 元 规格：
50 g
产品信息
概述| 货号 | 18646-50g |
| 描述 | Hesperidin is a flavanone rutinoside first isolated from citrus peels. It is metabolized by intestinal bacteria to an aglycone form, hesperetin (Item No. 10006084), which is thought to be more bioavailable due to reduced polarity that allows for increased cell permeability.1,2 At 100 µM, hesperidin has been shown to increase the cytotoxicity of doxorubicin (Item No. 15007) on MCF-7 and HeLa cancer cells in vitro by inhibiting cell cycle progression and upregulating apoptosis.1 It also is reported to produce estrogenic effects, decreasing serum and hepatic lipid concentrations and reducing osteoporosis in ovariectomized rats.1 Hesperidin produces free radical scavenging activity in various in vitro antioxidant assays.1 |
| 别名 | Cirantin;Hesperidoside;NSC 44184; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Meiyanto, E.,Hermawan, A., and Anindyajati. Natural products for cancer-targeted therapy: Citrus flavonoids as potent chemopreventive agents. Asian Pac.J.Cancer Prev. 13(2), 427-436 (2012).
2.Serra, H.,Mendes, T.,Bronze, M.R., et al. Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones. Bioorganic & Medicinal Chemistry 16(7), 4009-4018 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 610.6 |
| 分子式 | C28H34O15 |
| CAS号 | 520-26-3 |
| 稳定性 | ≥ 2 years |
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